Jung K, Kim SH, Joo KM, et al. WebAutoimmune diseases (your bodys immune system attacks its own tissue) can damage collagen. Koizumi S, Inoue N, Sugihara F, Igase M. Effects of collagen hydrolysates on human brain structure and cognitive function: A pilot clinical study. Effect of calcium and vitamin D supplementation with and without collagen peptides on bone turnover in postmenopausal women with osteopenia. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Additionally, some people may be allergic to collagen or have an intolerance to it. While they're way gentler than retinoids are, they can still cause a rash. View abstract. Alcock RD, Shaw GC, Tee N, Welvaert M, Burke LM. Kumar S, Sugihara F, Suzuki K, Inoue N, Venkateswarathirukumara S. A double-blind, placebo-controlled, randomised, clinical study on the effectiveness of collagen peptide on osteoarthritis. Speak with a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Osteoarthritis. Bookshelf Before View abstract. Most collagen users do not experience any adverse effects when taking a high-quality collagen supplement at the proper dosage. It's found in our tendons, ligaments, skin, muscles, bones, and blood vesselsand it plays a vital role in maintaining our overall structural integrity. The .gov means its official. and transmitted securely. These include: Collagen peptide supplements can offer a range of benefits from improved skin health to a reduction in joint pain and stronger hair and nails. Also, in many cases, the collagen is hydrolyzed. Nutrients. Most collagen supplements are not vegan or vegetarian friendly. As with any supplement, collagen supplements do have some potential side effects, especially when taken in excess. View abstract. de Miranda RB, Weimer P, Rossi RC. Maia Campos PMBG, Melo MO, Siqueira Csar FC. Efficacy and Safety of Topical or Oral Hydrolyzed Collagen in Women with Dermatoporosis: A Randomized, Double-Blind, Factorial Design Study. 2018;13(4):438-52. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Hakuta A, Yamaguchi Y, Okawa T, Yamamoto S, Sakai Y, Aihara M. Anti-inflammatory effect of collagen tripeptide in atopic dermatitis. Mar Drugs. Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S. Skin Pharmacol Physiol. It's possible to be sensitive or allergic to certain collagen Chemical additives in collagen peptide supplements, such as anti-caking substances and preservatives are common causes of acne flare-ups in those who notice increased breakouts with collagen use. 2016;96(12):4077-81. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. The https:// ensures that you are connecting to the One thing that you can look for is a medical grade collagen supplement like ProT Gold., It is still a possibility that you may experience some side effects with any collagen supplement. official website and that any information you provide is encrypted Read on to learn more about L-tryptophan, including its safety and efficacy. Oral Intake of Enzymatically Decomposed AP Collagen Peptides Improves Skin Moisture and Ceramide and Natural Moisturizing Factor Contents in the Stratum Corneum. Then, we recommend you evaluate the supplement itself along with the dosage you have been using., Not all collagen supplements are created equal and whether collagen can cause headaches may have more to do with the type of collagen you use and its bioavailability to you., When looking at the quality of a collagen supplement, first and foremost check to see if the company can back up their claims., If a company is making any kind of result claims regarding collagens ability to help resolve issues (especially medical issues) then they need to have resources, case studies, and other research to back up these claims., Since the FDA does not regulate collagen supplements as closely as they should, a lot of this is left up to the consumer to identify and sift through. Whey protein but not collagen peptides stimulate acute and longer-term muscle protein synthesis with and without resistance exercise in healthy older women: a randomized controlled trial. sharing sensitive information, make sure youre on a federal The vegan options may not be available everywhere, but many are available online. There is some evidence to suggest that collagen supplements can help with restoring or preventing the deterioration of the cartilage in the joints. View abstract. Conclusions and Relevance: Preliminary results are promising for the short and long-term use of oral collagen supplements for wound healing and skin aging. Effectiveness of eye movement exercise and diaphragmatic breathing with jogging in reducing migraine symptoms: A preliminary, randomized comparison trial. One review of the research into collagen supplementation found that using hydrolyzed collagen supplements helps promote joint health and potentially restore some bone density in people with osteoporosis and osteoarthritis. Apweiler E, Wallace D, Stansfield S, Allerton DM, Brown MA, Stevenson EJ, Clifford T. Sports (Basel). In this study, the women took either a collagen supplement or placebo for 8 weeks. So, these additional things are more often associated with certain side effects like an upset stomach. Unable to load your collection due to an error, Unable to load your delegates due to an error. If you take more collagen than your body can digest, it will cause problems adapting the body to new levels of energy. OTHER NAME(S): Collagen Hydrolysate, Collagen Peptidesi, Collagn, Collagen peptides have most often been used by adults in doses of 2.5-10 grams daily for up to 6 months. View abstract. Urinary Hydroxyproline Is Only Suitable As a Biomarker for Acute Intake, Up to 6 hr Postingestion of Collagen Proteins in "Free-Living," Healthy, Active Males. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Semin Arthritis Rheum. Argyrou C, Karlafti E, Lampropoulou-Adamidou K, et al. Effect of dietary supplementation with collagen hydrolysates on bone metabolism of postmenopausal women with low mineral density. 2020;20(1):12-17.View abstract. The takeaway Peptides are amino acids that are the building blocks of certain proteins needed by the skin, like collagen and elastin. Zdzieblik D, Jendricke P, Oesser S, Gollhofer A, Knig D. The Influence of Specific Bioactive Collagen Peptides on Body Composition and Muscle Strength in Middle-Aged, Untrained Men: A Randomized Controlled Trial. The effects of collagen peptides on muscle damage, inflammation and bone turnover following exercise: a randomized, controlled trial. Am J Med Sci. For most people, taking collagen peptide supplements should not have any major effects or health consequences, and topical collagen peptide products in particular are unlikely to pose a risk. Are they suitable for vegans and vegetarians? Licensed Natural Health Products Database. The question that often arises in the minds of people before consuming it is, Can collagen cause diarrhea? The answer to this Oral collagen supplementation for skin aging: A fad or the future? Also, as with any supplement, the Food and Drug Administration (FDA) do not evaluate any claims that a company makes on how well their collagen product works. Drugs. WebCollagen comprises about 60% of cartilage, a very firm tissue that surrounds bones and cushions them from the shock of high-impact movements; so a breakdown in collagen could lead to a loss of cartilage and joint problems. The https:// ensures that you are connecting to the This means that the manufacturer has broken the collagen in the supplements down into peptides, making it easier for the body to absorb and use. -CTX and P1NP were unaffected by CP supplementation (P > 0.05). Alipoor E, Hosseinzadeh-Attar MJ, Salehi S, et al. Sci Rep. 2022 Jun 13;12(1):9804. doi: 10.1038/s41598-022-14068-2. When choosing your collagen peptides supplement, be sure its manufacturer hasnt been called out by the FDA. We currently have no information for COLLAGEN PEPTIDES overview. View abstract. Wauquier F, Boutin-Wittrant L, Bouvret E, Le Faouder J, Roux V, Macian N, Pickering G, Wittrant Y. Nutrients. Collagen peptides powder may also cause headaches, dizziness, or lightheadedness in some users. pii: E1356. J Cosmet Dermatol. Others may experience side effects causing issues with the skin or digestive system, among other problems, but the likelihood of this is based largely on the quality of your chosen collagen peptides product. A person should always talk to their doctor before starting any new supplements or increasing the use of any existing supplement. Best overall collagen supplement: Vital Proteins Collagen Peptides. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. People can consume collagen supplements they purchase from a number of online and local stores, and they can usually find a type that matches their specific dietary needs. 2021;20(1):188-194. While we have no reports of ProT Gold users experiencing headaches or migraines after using our collagen products, preliminary research into the topic suggests that there may be a correlation between some collagen supplements and headaches., Whether collagen can cause headaches or not often is dependent on the person taking the supplement, the dosage, the type of collagen, and the supplement quality itself., If you suspect that your supplemental collagen can cause headaches or migraines, then exploring why you have this reaction and how to prevent it will be the first place to start., Before we get into whether collagen can cause headaches, lets look at the overall safety of collagen supplements in general., If youre asking the question: can collagen cause headaches? You are probably also interested in other possible side effects of collagen, and if collagen is a safe supplement to take., Its hard to answer whether collagen can cause headaches and if the supplement itself is safe, simply because the FDA does not regulate most supplements., Since there is such limited regulation of supplements on the market, this leads to immense skepticism regarding how safe they really are and what side effects they cause., The lack of regulation when it comes to supplements versus drugs means that not all supplement companies necessarily have to prove their claims., So, if they are simply trying to sell a product to the consumer, they do not have to have evidence to support whether or not the collagen supplement they are providing actually will benefit the consumer, or whether their supplemental collagen can cause headaches or other issues., Still, the FDA does recognize ingestible collagen as Generally Recognized As Safe (GRAS)., There have been specific collagen supplements that have been recalled by the FDA for safety reasons, which is why it is important to buy from a reputable brand., For instance, our liquid collagen supplement, ProT Gold, is actually recognized as a medical food, which is why it has a nutritional label, not a supplement label., Because of this, ProT Gold is also trusted by over 3,000 medical facilities and used widely for medical nutrition therapy., Something that should be recognized about collagen as a supplement is that it is natural. Some collage supplements do source from these animals, so when taking them, youre likely to have an allergic reaction of some kind., The question of whether collagen can cause headaches or not is somewhat subjective, but the short answer is yes. Brain Behav. For more in-depth resources about vitamins, minerals, and supplements, visit our dedicated hub. 2022 Nov 25;14(23):5027. doi: 10.3390/nu14235027. WebMD does not provide medical advice, diagnosis or treatment. 2022 Dec 17;12(12):1283. doi: 10.3390/metabo12121283. Oliviero F, Ramonda R, Hoxha A, et al. Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients. Jendricke P, Centner C, Zdzieblik D, Gollhofer A, Knig D. Specific Collagen Peptides in Combination with Resistance Training Improve Body Composition and Regional Muscle Strength in Premenopausal Women: A Randomized Controlled Trial. Sangsuwan W, Asawanonda P. Four-weeks daily intake of oral collagen hydrolysate results in improved skin elasticity, especially in sun-exposed areas: a randomized, double-blind, placebo-controlled trial. Miyanaga M, Uchiyama T, Motoyama A, Ochiai N, Ueda O, Ogo M. Oral Supplementation of Collagen Peptides Improves Skin Hydration by Increasing the Natural Moisturizing Factor Content in the Stratum Corneum: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. 2018;10(7).View abstract. A pilot study for the detection of cyclic prolyl-hydroxyproline (Pro-Hyp) in human blood after ingestion of collagen hydrolysate. 2018;10(1). Collagen is a protein that our body already produces, so when taking it in a supplement form, you are replenishing your collagen stores with animal-based collagen., Since it is something that your body already recognizes and needs, the risk is relatively minimal and there are few health concerns about how collagen reacts within your body., Now, this isnt to say that there are no side effects, allergy concerns, or risks involved in taking a collagen supplement., Introducing any new supplement into your diet should be done so with the consultation of a medical professional, especially if you are taking prescription medications, are pregnant, or have any underlying health conditions., Every person taking a supplement may have a different reaction when introducing it into their diet. Although collagen peptide supplements are typically considered safe, and there are not many known risks, many supplements are made from potential food allergens such as fish, shellfish and eggs, so its best to avoid these products if you are prone to such allergic reactions. Its always something 2009;60 Suppl 2:99-113. Apart from fatigue, this might lead to headaches and feelings of nervousness and irritability. The two most commonly proposed benefits of collagen peptides are improved skin health and reduced joint pain. Health Canada. Daily oral supplementation with collagen peptides combined with vitamins and other bioactive compounds improves skin elasticity and has a beneficial effect on joint and general wellbeing. Epub 2013 Dec 24. View abstract. Skin rashes. Insulin is an example of a peptide drug, which is composed of 51 amino acids. Collagen supplements can help improve skin health. It is responsible for several biological functions, one of which is to provide structural support in connective tissue, muscle, and skin. WebThis study examined whether consuming collagen peptides (CP) before and after strenuous exercise alters markers of muscle damage, inflammation and bone turnover. FOIA Asserin J, Lati E, Shioya T, Prawitt J. Hydroxyproline, (a key amino acid found in that collagen), can be converted into oxalate and excreted through the kidneys. government site. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis. Another similar study in the journal Skin Pharmacology and Physiology looked at the effects of collagen supplements on womens skin. If youre in a state of chronic migraine or get attacks often, I recommend avoiding collagen peptides unless its prescribed by your physician. Nutrition is a key factor influencing skin health and consequently its appearance. Arch Acad Emerg Med 2021;9(1):e50. Although some experts believe that peptide skin creams or moisturizers are not able to be absorbed fully via the skin, instead recommending oral supplements, some research has nonetheless shown them to have positive effects on skin health. Nutrients 2018;10(10). Clin Interv Aging. However, it might also help promote other areas of health, such as bone, joint, and heart health. Li X, He Z, Xu J, Su C, Xiao X, Zhang L, Zhang H, Li H. Foods. When taken by mouth, collagen peptides seem to build up in the skin and cartilage. View abstract. FOIA 2005 - 2023 WebMD LLC. Yes. The .gov means its official. Collagen is one of the most plentiful proteins in mammals. Prowting JL, Bemben D, Black CD, Day EA, Campbell JA. Appl Physiol Nutr Metab. Main benefits: Provides moisture to the skin and scalp, strengthens the hair follicle, accelerates healing, and nourishes the hair bulb.